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34 Arq Asma Alerg Imunol – Vol. 2. N° 1, 2018 ações graves e de anafilaxia induzida por exercício dependente de alimento, no caso o trigo 162 . Outras Embora na prática clínica a hipersecreção brônqui- ca, as otites de repetição e a língua geográfica sejam frequentemente atribuídas à alergia alimentar, não há consenso na literatura, não devendo, portanto, estas manifestações serem atribuídas à alergia alimentar. Assim, é necessária a busca de causas etiológicas para estas manifestações, não se justificando a intro- dução de dietas restritivas a estes pacientes. Doenças inflamatórias intestinais também têm sido atribuídas à alergia alimentar (doença de Crohn e colite ulcerativa), e embora esta hipótese seja atra- ente, estudos são necessários para documentar essa possibilidade ainda não comprovada 163 . Alguns estudos têm sugerido que a artrite crônica pode estar relacionada à alergia alimentar, mas ape- nas em alguns poucos casos pôde se comprovar esta relação, por meio de teste de provocação oral com alimento suspeito de modo duplo cego e controlado por placebo 163 . De modo similar, outros distúrbios ou sintomas foram relacionados à ingestão de alimentos ou aditivos alimentares. São eles a enxaqueca ou a epilepsia após ingestão de um determinado alimen- to ou a hiperatividade 148 . Em todos esses casos há necessidade de maior comprovação que firme o diagnóstico de alergia alimentar. A relação entre transtorno do espectro autista e alergia alimentar não foi confirmada 165-167 . 1. Sampson HA. Food allergy: past, present and future. Allergol Int. 2016;65(4):363-9. 2. Gibson PR. History of the low FODMAP diet. J Gastroenterol Hepatol. 2017;32(Suppl 1):5-7. 3. Tordesillas L, BerinMC, Sampson HA.Immunology of Food Allergy. Immunity. 2017;47(1):32-50. 4. 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